ABSTRACT Microbial gene clusters encoding the biosynthesis of primary and secondary metabolites play key roles in shaping microbial ecosystems and driving microbiome-associated phenotypes.Although effective approaches exist to evaluate the metabolic potential of such bacteria through identification of these metabolic gene clusters in their genomes,
RAS mutations are among the most common oncogenic mutations in human cancers.Among RAS mutations, KRAS has the highest frequency and is present in almost 30% of non-small-cell lung cancer (NSCLC) patients.Lung cancer is the number one cause of mortality among cancers as a consequence of outrageous aggressiveness and late Probiotics diagnosis.High m
BackgroundHuman pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) show tremendous promise for cardiac regeneration following myocardial infarction (MI), but their transplantation gives rise to transient ventricular tachycardia (VT) in large-animal MI models, representing a major hurdle Wallets/Money Clips to translation.Our group previously r
We develop a three-step computing approach to explore a hierarchical ranking network for a society of captive rhesus macaques.The computed network is sufficiently informative to address the question: Is the ranking network for a rhesus macaque society more like a kingdom or a corporation? Our computations are based on a three-step approach.These st